Even though we have talked quite a bit about POGO on our 64-bit sessions, we seldom have mentioned how you can actually weigh down the profiles that you use. In order to find this information, check this link at the MSDN site that explains everything.
If you want to 'take it up a notch' when it comes to POGO and find exactly what is happening with your scenarios, check this blog post from Kang Su Gatlin.
If there is anything you would like to know about POGO, just let me know and I'll more than happy to research it for you!